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IFNalpha在体内激活休眠的造血干细胞

Marieke A G Essers1, Sandra Offner, William E Blanco-Bose

  • 1Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

Nature
|February 13, 2009
PubMed
概括

干扰素-α (IFNalpha) 可以唤醒休眠的造血干细胞 (HSCs) 繁殖,但长期暴露会损害它们的功能. 这一发现为向癌症干细胞提供了潜在的新策略.

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