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鉴定了一种树突细胞受体,该受体将感知亡与免疫结合在一起

David Sancho1, Olivier P Joffre, Anna M Keller

  • 1Immunobiology Laboratory, London Research Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

Nature
|February 17, 2009
PubMed
概括

死细胞会触发免疫反应. CD8alpha+树突细胞使用CLEC9A来感知这些细胞,启动T细胞原始化. 这一发现对于理解移植中的免疫力和癌症排斥至关重要.

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