敏感有机金属化合物的催化化通过对抗性N/B路易斯对催化剂系统
Kirill V Axenov1, Gerald Kehr, Roland Fröhlich
1Organisch-Chemisches Institut der Universität Münster, Corrensstrasse 40, 48149 Münster, Germany.
Journal of the American Chemical Society
|February 20, 2009
概括
一个新的氧复合物和三氧化物形成了一个"对抗性"的易斯对. 这对通过独特的过程有效地催化了体积庞大的 imines 和 silyl enol 以太的化.
科学领域:
- 有机金属化学 有机金属化学
- 催化剂是一种催化剂.
- 化反应 化反应
背景情况:
- 复合物是有机合成中的多功能催化剂.
- 易斯对,特别是"对抗性"的对,提供独特的反应概况.
- 硬质阻碍基板的高效化仍然是一个挑战.
研究的目的:
- 为了研究 bis ((arylimino-Cp) ZrCl2复合物与 B ((C6F5) 3.3) 的反应性.
- 在化反应中探索由此产生的易斯对的催化潜力.
- 开发用于体积较大的 imines 和 silyl enol ethers 的高效催化系统.
主要方法:
- 在 bis ((arylimino-Cp) ZrCl2 (I) 和 B ((C6F5) 3.3) 之间形成一个"对抗性的"易斯对.
- 易斯对与二的反应形成化产物 (II).
- 对盐III的催化活性进行评价,以化大胺和乙醇.
主要成果:
- 双利米诺-CpZrCl2复合体和BC6F5) 3形成一个反应性"对抗性"的易斯对.
- 二处理导致氨基甲基-Cp化产物 (II) 的准自催化生成.
- 由此产生的盐 (III) 在催化大量伊胺和乙醇乙烯的化过程中表现出高效率.
结论:
- "对抗性"的易斯对系统对二具有独特的反应性.
- 基于盐III的催化系统对于化绝缘要求高的基板是有效的.
- 这项研究提出了一种新的方法,用于利用基于的易斯对进行催化化.
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