在低收入母亲中,糖尿病和围产期抑郁症之间存在关联
Katy Backes Kozhimannil1, Mark A Pereira, Bernard L Harlow
1Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusett, USA.
JAMA
|February 27, 2009
概括
怀孕期间患有糖尿病的妇女面临近两倍的围产期抑郁症的风险. 这包括产后抑郁症的新病例,突出了糖尿病和母亲心理健康之间的关键联系.
科学领域:
- 生殖健康 生殖健康
- 内分泌学 在内分泌学.
- 围产阶段精神病学 围产阶段精神病学
背景情况:
- 围产期抑郁症影响10-12%的新.
- 糖尿病导致约9%的怀孕并发症.
- 现有研究表明,糖尿病患者患重度抑郁症的患病率更高.
研究的目的:
- 调查糖尿病 (怀孕或孕期) 与围产期抑郁症之间的联系.
- 在一组低收入女性中研究这种关联.
- 为了评估怀孕期间和产后期的抑郁症.
主要方法:
- 使用新泽西州医疗补助行政索赔数据进行回顾性队列研究.
- 包括2004年7月至2006年9月间分娩的11,024名妇女.
- 评估糖尿病和抑郁症使用诊断代码和处方要求在分娩周围的定义时间内.
主要成果:
- 在调整后,患有糖尿病的女性患儿周围抑郁症的几率几乎翻了一番 (OR,1.85;95% CI,1.45-2.36).
- 15.2%的糖尿病女性患有抑郁症,而没有糖尿病的女性则为8.5%.
- 患有糖尿病且没有产前抑郁症的妇女,产后抑郁症诊断或使用抗抑郁药的几率更高 (OR,1.69;95% CI,1.27-2.23).
结论:
- 怀孕前期和妊娠期糖尿病独立地与围产期抑郁症有关.
- 糖尿病增加了新出现产后抑郁症的风险.
- 这些发现对于低收入的母体人口来说具有意义.
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