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Updated: May 9, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio
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Published on: August 24, 2013

在IHH中引起数字异常的突变会改变其信号容量和范围

Bo Gao1, Jianxin Hu, Sigmar Stricker

  • 1Department of Biochemistry, the University of Hong Kong, Hong Kong, China.

Nature
|March 3, 2009
PubMed
概括

甲状腺骨类型A1 (BDA1),是一种影响手指和脚骨的遗传疾病,是由印度刺 (IHH) 基因的突变引起的. 一种特定的IHH突变损害了信号传输,导致小鼠的发育异常,反映了人类BDA1.1.

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