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Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids
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第二种类型脂肪酸合成不是适合的抗生素点,用于阳性病原体

Sophie Brinster1, Gilles Lamberet, Bart Staels

  • 1Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France.

Nature
|March 6, 2009
PubMed
概括

针对脂肪酸合成II (FASII) 途径的抗生素开发是有缺陷的. 外源性脂肪酸,就像人体血清中的脂肪酸一样,允许细菌绕过FASII抑制,使这些药物对阳性感染无效.

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