心脏肌结合蛋白C突变和高性心肌病:哈普洛缺陷,乱的酸化和心肌细胞功能障碍

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Updated: Jun 23, 2026

An Approach to Study Shape-Dependent Transcriptomics at a Single Cell Level
06:02

An Approach to Study Shape-Dependent Transcriptomics at a Single Cell Level

Published on: November 2, 2020

Sabine J van Dijk1, Dennis Dooijes, Cris dos Remedios

  • 1Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands.

Circulation
|March 11, 2009
PubMed
概括

由MYBPC3突变引起的家族性缩性心肌病导致心脏肌结合蛋白C (cMyBP-C) 表达减少,心肌细胞收缩性受损. 这种功能障碍导致最大力降低和敏感度变化.

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