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特定的核酸与纳米孔上捕获的单个DNA聚合酶复合体结合和重新结合

Nicholas Hurt1, Hongyun Wang, Mark Akeson

  • 1Department of Chemistry and Biochemistry, Baskin School of Engineering, University of California, Santa Cruz, California 95064, USA.

Journal of the American Chemical Society
|March 12, 2009
PubMed
概括

单分子纳米孔分析显示,DNA聚合酶在电场下保持功能. 这使得DNA合成的实时监测成为可能,这对于理解酶动力学和忠实性至关重要.

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