在Arabidopsis thaliana中对胚胎模式的父亲控制
Martin Bayer1, Tal Nawy, Carmela Giglione
1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Science (New York, N.Y.)
|March 17, 2009
概括
通过精子细胞传递的SHORT SUSPENSOR (SSP) 基因激活了Arabidopsis中的YODA (YDA) 途径. 这种父效应调节了胚胎的第一个不对称的分裂,这对胚胎发育至关重要.
科学领域:
- 植物发育生物学植物发育生物学
- 分子遗传学 分子遗传学
- 细胞信号传递 细胞信号传递
背景情况:
- YODA (YDA) 途径对于阿拉比多普西斯菌根的延长和悬浮体的发展至关重要.
- 家长的起源效应,即基因的家长来源影响其表达,在植物中是已知的,但机制往往不清楚.
研究的目的:
- 研究 SHORT SUSPENSOR (SSP) 基因在调节YDA通路中的作用.
- 阐明SSP作用的机制,特别是关于其母源效应.
主要方法:
- 在Arabidopsis中SSP转录和蛋白质定位的分析.
- 调查SSP对YDA依赖信号的影响.
- 研究SSP转录的父亲遗传的作用.
主要成果:
- SSP转录在花粉中产生,但通过精子细胞传递到胚胎和内体后被翻译.
- 在受精后,SSP蛋白暂时积累,激活依赖YDA的信号传递.
- 宫外SSP表达激活了YDA信号,证实了它的作用.
结论:
- SSP作为YDA通路的父性印记调节器.
- 父亲的SSP蛋白为胚胎的第一个不对称的分裂提供了一个时间线索.
- 这项研究揭示了一种新型的原始亲子机制,控制了Arabidopsis.的早期胚胎模式.
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