可可和心血管健康
Roberto Corti1, Andreas J Flammer, Norman K Hollenberg
1Cardiovascular Center, Cardiology, University Hospital, Raemistrasse 100, CH-8091 Zurich, Switzerland. roberto.corti@usz.ch
Circulation
|March 18, 2009
概括
可可的消费可以通过有益于血压和血管功能来改善心血管健康. 进一步的研究探索其机制,包括氧化激活和抗氧化作用,以寻找潜在的临床应用.
科学领域:
- 心血管科学 心血管科学
- 营养流行病学 营养流行病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 饮食中的植物性食品与降低冠状动脉疾病和中风等心血管疾病的风险有关.
- 可可被认为是这些心脏保护作用的潜在媒介.
- 新兴研究表明,可可对血压,胰岛素抵抗和血管/血小板功能产生积极影响.
研究的目的:
- 审查现有关于可可对心血管的影响的数据.
- 概述了可可的益处背后的拟议机制.
- 突出可可消费的潜在临床影响.
主要方法:
- 流行病学和实验研究的文献综述.
- 对拟议的生物途径进行分析.
- 对临床结果的当前证据的综合.
主要成果:
- 流行病学研究支持植物性食品 (包括可可) 与降低心血管风险之间的联系.
- 可可消费对血压,胰岛素敏感性和内皮功能产生有益影响.
- 潜在的机制包括氧化路径激活,抗氧化和抗炎作用.
结论:
- 可可的消费表明有希望的心血管益处.
- 机制包括改善内皮功能和减少氧化应激.
- 需要进行进一步的研究,以确定心血管健康管理中可可摄入量的临床指南.
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