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在B型肝炎病毒复制细胞中识别过多的胆固醇前体,通过非向的脂质代谢物分析

Mary A Rodgers1, Alan Saghatelian, Priscilla L Yang

  • 1Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA.

Journal of the American Chemical Society
|March 24, 2009
PubMed
概括

乙型肝炎病毒 (HBV) 感染在宿主细胞中选择性地增加7-脱胆固醇 (7-DHC),一种胆固醇前体. 这一发现表明病毒可能利用特定的类固醇,为抗病毒药物发现开辟了新的途径.

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