年龄对冠状动脉手术结果的影响
W S Weintraub1, J M Craver, C L Cohen
1Division of Cardiology, Emory University School of Medicine, Atlanta, GA.
Circulation
|November 1, 1991
概括
晚年显著增加了冠状动脉手术后并发症和死亡的风险. 糖尿病和高血压等危险因素也起作用,但年龄是最强的预测因素.
科学领域:
- 心血管外科心血管外科
- 老年医学 老年医学
- 健康 结果 研究 研究 结果
背景情况:
- 冠状动脉外科手术越来越多地在老年人和更生病的患者身上进行.
- 年龄作为并发症和死亡率的预测因素需要进一步评估.
研究的目的:
- 评估患者年龄对预测冠状动脉旁路移植 (CABG) 后并发症和死亡率的影响.
主要方法:
- 对13625名接受冠状动脉手术的患者进行了回顾性分析.
- 根据年龄组对患者进行分层 (例如40-49岁,50-59岁,60-69岁,70-79岁,80岁以上).
- 多变量分析以确定不良结果的独立相关性.
主要成果:
- 40岁后的每十年,并发症和死亡率都会增加.
- 高龄是神经事件,伤口感染和死亡的最强的独立预测因素.
- 死亡的其他显著相关因素包括新出现的手术,女性性别和充血性心力衰竭史.
- 周围手术性心肌梗塞不依赖年龄,但与突发性手术有很强的相关性.
结论:
- 年龄是预测冠状动脉手术后结果的关键因素.
- 风险分层模型应纳入先进的年龄和其他已识别的相关因素.
- 进一步的研究可能会完善对接受CABG的老年患者的风险预测.
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