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由 peracids 和其他氧化氧化剂诱导的 DNA 中的 iminohydantoin 损伤

Wenjie Ye1, R Sangaiah, Diana E Degen

  • 1Department of Environmental Sciences and Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

Journal of the American Chemical Society
|April 10, 2009
PubMed
概括

一个新的DNA损伤,5-carboxamido-5-formamido-2-iminohydantoin (2-Ih),是由 peracids 的瓜氧化形成的. 这种稳定的2-I损伤可以作为潜在的体内生物标志物.

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