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In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice
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在沙飞载体中,在Leishmania的循环发育过程中证明了基因交换

Natalia S Akopyants1, Nicola Kimblin, Nagila Secundino

  • 1Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Science (New York, N.Y.)
|April 11, 2009
PubMed
概括

莱什曼尼亚寄生虫在沙中进行性繁殖,产生杂交后代. 这种遗传交换有助于寄生虫的多样性,并有助于研究药物耐药性等特征.

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Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...