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Updated: Jun 16, 2026

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血小板矩阵金属蛋白酶-1通过激活PAR1在一个神秘的连接体位点来调解血栓生成

Vishal Trivedi1, Adrienne Boire, Boris Tchernychev

  • 1Department of Medicine, Tufts University School of Medicine, Molecular Oncology Research Institute, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA.

Cell
|April 22, 2009
PubMed
概括

血小板矩阵金属蛋白酶-1 (MMP-1) 激活了血小板上的蛋白酶激活受体-1 (PAR1),促进了聚合. 阻止这种MMP-1-PAR1相互作用可能会预防动脉血栓形成.

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