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Updated: Jun 23, 2026

Using Modified Synthetic Oligonucleotides to Assay Nucleic Acid-Metabolizing Enzymes
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Published on: July 5, 2024

锁定核酸 (LNA) 修饰的二核酸mRNA盖模拟物:合成,酶内置和利用

Anilkumar R Kore1, Muthian Shanmugasundaram, Irudaya Charles

  • 1Life Technologies Corporation, Bioorganic Chemistry Division, 2130 Woodward Street, Austin, Texas 78744-1832, USA. anil.kore@lifetech.com

Journal of the American Chemical Society
|April 24, 2009
PubMed
概括

一种新型的锁定核酸 (LNA) 修改的帽子模拟物增强了信使RNA (mRNA) 的稳定性和翻译效率,显示了基于RNA的疫苗和生物化学研究的前景.

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