相关实验视频
出生时的复苏和8岁时的认知:一个队列研究
David E Odd1, Glyn Lewis, Andrew Whitelaw
1Clinical Science at North Bristol, University of Bristol, Bristol, UK. david.odd@nbt.nhs.uk
Lancet (London, England)
|April 24, 2009
概括
即使没有脑病变迹象,出生时被复苏的婴儿也面临着较低儿童智商 (IQ) 得分的更高风险. 这突显了新生儿复苏的潜在长期认知影响.
科学领域:
- 新生儿护理和发育儿科
背景情况:
- 产后复苏可能会导致细微的认知缺陷,在儿童时期晚些时候可以检测到.
- 在没有明显的神经症状的婴儿中,复苏的长期认知影响尚未完全理解.
研究的目的:
- 调查是否婴儿需要在出生时复苏,但仍然无症状的脑病变在童年时表现出智商 (IQ) 分数的下降.
主要方法:
- 一项对10609名婴儿的队列研究,来自Avon长度研究的父母和孩子进行了.
- 分析了三个组:复苏无症状的婴儿 (n=815),复苏脑病的婴儿 (n=58) 和一个非复苏的参考组 (n=10,609).
- 认知功能,特别是智商,在平均年龄为8.6岁时使用儿童缩短的韦施勒智力表 (WISC-III) 进行评估.
主要成果:
- 复苏的婴儿,无论是无症状的 (OR 1.65) 还是脑病变的 (OR 6.22),在8岁时都有较低智商得分 (<80) 的风险增加.
- 由于复苏而导致低智商的人口可归因风险分数在无症状婴儿 (3.4%) 和脑病 (1.2%) 相比,在无症状婴儿中更高.
结论:
- 新生儿复苏与儿童IQ得分较低的风险增加有关,无论最初的神经症状如何.
- 接受复苏的无症状婴儿可能比那些发展出明显脑病变的婴儿更大比例的人口具有低智商.
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