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Updated: Jun 23, 2026

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
10:44

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures

Published on: March 28, 2017

电化学驱动的药物代谢是由含有人类细胞染色体P450的膜驱动的

Yasuhiro Mie1, Masaaki Suzuki, Yasuo Komatsu

  • 1Research Institute of Genome-based Biofactory, National Institute of Advanced Industrial Science and Technology, 2-17-2-1 Tsukisamu-higashi, Sapporo 062-8517, Japan. yasuhiro.mie@aist.go.jp

Journal of the American Chemical Society
|May 1, 2009
PubMed
概括

这项研究证明了在微粒中使用人类细胞染色体P450s (CYPs) 的电化学驱动药物代谢. 这种新的方法通过直接向CYP酶提供电子,为药物开发提供了快速分析.

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Published on: March 20, 2018

Single Liposome Measurements for the Study of Proton-Pumping Membrane Enzymes Using Electrochemistry and Fluorescent Microscopy12:15

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Published on: February 21, 2019

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