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Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
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通过NR2子单元对NMDA受体活性进行差异控制的机制

Marc Gielen1, Beth Siegler Retchless, Laetitia Mony

  • 1Laboratoire de Neurobiologie, Ecole Normale Supérieure, CNRS, 46 rue d'Ulm, 75005 Paris, France.

Nature
|May 1, 2009
PubMed
概括

这项研究揭示了NR2氨基终端域 (NTD) 控制N-甲基-D-酸盐受体 (NMDAR) 亚型活性. 这种NTD驱动的关门机制为药物提供了一个新的目标,用于调节NMDAR在脑疾病中的功能.

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