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Updated: Jun 23, 2026

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
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一个全基因组支持的精神病变体的神经机制

Christine Esslinger1, Henrik Walter, Peter Kirsch

  • 1Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, J5, 68159 Mannheim, Germany.

Science (New York, N.Y.)
|May 2, 2009
PubMed
概括

在ZNF804A (rs1344706) 中一个常见的遗传变异会影响健康个体的大脑连接. 这种基因功能合的剂量依赖性改变,特别是在背侧前额叶皮质,表明精神病的神经遗传风险机制.

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