坎帕尼亚哈德罗萨尔B. canadensis的生物分子表征和蛋白质序列
Mary H Schweitzer1, Wenxia Zheng, Chris L Organ
1North Carolina State University, Raleigh, NC 27695, USA. schweitzer@ncsu.edu
Science (New York, N.Y.)
|May 2, 2009
概括
固有蛋白质,包括原蛋白,被保存在一个8000万年前的哈德罗索尔,Brachylophosaurus canadensis. 这一发现支持了鸟恐龙进化联系,并证实恐龙中的分子保存并不罕见.
科学领域:
- 古生物学的古生物学
- 分子生物学分子生物学
- 生物化学 生物化学
背景情况:
- 非鸟类恐龙的内源性分子材料的保存是正在进行的科学辩论的主题.
- 以前的发现表明,分子保存可能是罕见的,特定标本的证据有限.
研究的目的:
- 为了调查坎帕尼亚海德罗萨尔标本中保存的内源性蛋白质的存在和性质.
- 为了提供进一步的证据支持或反对在白纪恐龙中广泛的分子保存.
- 利用遗传学分析来确认保存的原蛋白的内源来源.
主要方法:
- 骨碎片和软组织的微观结构分析.
- 免疫学测定检测特定蛋白质.
- 质谱测量对原蛋白的测序.
- 遗传学分析以确定进化关系.
主要成果:
- 多种证据表明,在Brachylophosaurus canadensis中,内源性蛋白质物质的保存,包括骨基质和血管蛋白质.
- 对Brachylophosaurus原蛋白序列的遗传学分析强烈支持鸟类-恐龙类.
- 这些发现与保存的原蛋白的内源来源一致.
- 这些结果证实了Tyrannosaurus rex的早期发现,表明分子保存不是独一无二的.
结论:
- 固有的蛋白质性物质在一个8000万年前的哈德罗索尔中得到了明显的保存.
- 保持原蛋白支持鸟类和恐龙之间的进化联系.
- 纪恐龙的分子保存被证实是一种反复出现的现象,而不是孤立的事件.
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