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Updated: May 6, 2026

Deacetylation Assays to Unravel the Interplay between Sirtuins SIRT2 and Specific Protein-substrates
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SIRT5 脱乙化碳酸合成酶1并调节尿素循环

Takashi Nakagawa1, David J Lomb, Marcia C Haigis

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge, 02139, USA.

Cell
|May 5, 2009
PubMed
概括

塞尔图因5 (SIRT5) 激活了线粒体中的碳酸合成酶1 (CPS1),这对氨解毒至关重要. 缺少SIRT5会损害这一过程,导致在禁食和改变饮食期间氨水平升高.

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