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Updated: Jun 23, 2026

Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities
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基于胺的抑制剂的形状变异性

Xue Li1, Xiao He, Bing Wang

  • 1Department of Chemistry, Quantum Theory Project, 2328 New Physics Building, P.O. Box 118435, University of Florida, Gainesville, Florida 32611-8435, USA.

Journal of the American Chemical Society
|May 14, 2009
PubMed
概括

先进的量子力学/分子力学 (QM/MM) 改进提高了对小分子如何与蛋白质结合的理解,这对于基于结构的药物设计和优化药物亲和力至关重要.

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