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Updated: May 12, 2026

Detection of Trypanosoma brucei Variant Surface Glycoprotein Switching by Magnetic Activated Cell Sorting and Flow Cytometry
09:45

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Published on: October 19, 2016

一个表面传送器家族传递了三子体分化信号

Samuel Dean1, Rosa Marchetti, Kiaran Kirk

  • 1Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK.

Nature
|May 16, 2009
PubMed
概括

非洲睡眠病寄生虫使用环境线索来触发发育. 研究人员确定PAD蛋白对于感知这些信号和区分至关重要,作为关键的表面标记物.

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Membrane Transporters01:31

Membrane Transporters

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ABC Transporters: Exporter

ATP-binding cassette or ABC transporter is the largest superfamily of integral membrane proteins. The transporters have transmembrane-binding domains (TMDs) and nucleotide-binding domains (NBDs). The TMDs are specific to their substrates, whereas the NBDs are similar to engines that complete ATP hydrolysis to complete the substrate transport. They can be full transporters consisting of two TMDs and NBDs, half transporters with one TMD and NBD, while some encoded with a single TMD or NBD are...
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Cotranslational Protein Translocation

Translocation of proteins across membranes is an ancient process that occurs even in bacteria and archaebacteria. In fact, the components of the translocation machinery are still conserved between prokaryotes and eukaryotes.
Sec61 channel partners for cotranslational translocation
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Protein Translocation Machinery on the ER Membrane

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Sec61 protein conducting channel
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Protein Transport to the Thylakoids

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Carrier-Mediated Transport

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