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Updated: Jun 23, 2026

Production, Crystallization and Structure Determination of C. difficile PPEP-1 via Microseeding and Zinc-SAD
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由subangstrom X射线晶体学揭示的DING蛋白质的酸盐结合模式的解

Dorothee Liebschner1, Mikael Elias, Sèbastien Moniot

  • 1Cristallographie Resonnance Magnetique et Modelisations, CNRS UMR 7036 Nancy-Universite, 54506 Vandoeuvre-les-Nancy, France.

Journal of the American Chemical Society
|May 19, 2009
PubMed
概括

细菌蛋白PfluDING揭示了酸盐结合在酸盐溶性结合蛋白 (SBPs) 中的分子基础. 高分辨率结构显示了带正电荷的结合裂和12个键,这对于离子特异性至关重要.

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Protein Kinases and Phosphatases02:54

Protein Kinases and Phosphatases

Proteins undergo chemical modifications that trigger changes in the charge, structure, and conformation of the proteins. Phosphorylation, acetylation, glycosylation, nitrosylation, ubiquitination, lipidation, methylation, and proteolysis are various protein modifications that regulate protein activity. Such modifications are usually enzyme-driven.
Protein kinases
Many proteins in the cell are regulated by phosphorylation, the addition of a phosphate group. A family of enzymes called kinases...