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Updated: Jun 23, 2026

Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins
07:24

Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins

Published on: September 23, 2021

偏磁离子能够调整核放松率,并在蛋白质固态核磁共振中提供长距离的结构约束

Philippe S Nadaud1, Jonathan J Helmus, Stefanie L Kall

  • 1Department of Chemistry, The Ohio State University, Columbus, Ohio 43210, USA.

Journal of the American Chemical Society
|May 19, 2009
PubMed
概括

这项研究引入了一种新的方法,使用磁性离子通过神奇角度旋转的固态核磁共振 (SSNMR) 获得对蛋白质的远程结构洞察力. 铜-EDTA复合体通过调节核放松率来提供精确的结构约束,扩展SSNMR.

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