胰腺移植 胰腺移植
Steve A White1, James A Shaw, David E R Sutherland
1Department of Hepatopancreatobiliary and Transplantation Surgery, Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, UK. steve.white@nuth.nhs.uk
Lancet (London, England)
|May 26, 2009
概括
胰腺移植通过替代胰岛素注射,为患有功能衰竭的糖尿病患者提供了更好的生活质量. 尽管这是一项需要终身免疫抑制的大型手术,但它仍然是首选的内分泌替代疗法.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 移植手术 移植手术
背景情况:
- 胰腺移植已经作为内分泌替代疗法进行了40多年.
- 它是糖尿病患者经历末期功能衰竭的主要治疗方法.
- 手术技术和免疫抑制技术已经进步,扩大了移植指示.
研究的目的:
- 审查胰腺移植的指示,类别和结果.
- 评估胰腺移植对糖尿病长期并发症的影响.
- 讨论改善生活质量的好处与手术风险和免疫抑制的好处.
主要方法:
- 审查关于胰腺移植的现有文献.
- 对患者结果和长期并发症数据的分析.
- 讨论手术的进步和免疫抑制策略.
主要成果:
- 胰腺移植通过消除胰岛素依赖而显著改善生活质量.
- 该程序涉及重大手术,需要终身免疫抑制.
- 结果通常是有利的,对糖尿病的长期并发症有显著的影响.
结论:
- 胰腺移植仍然是选择末期功能衰竭的糖尿病患者的重要治疗方法.
- 手术和免疫抑制方案的持续进步提高了患者的治疗结果.
- 改善生活质量的好处必须与重大手术和终身药物治疗的风险进行权衡.
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