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糖系转移酶sxc/Ogt在多抑制中的重要作用

Maria Cristina Gambetta1, Katarzyna Oktaba, Jürg Müller

  • 1Gene Expression Programme, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg, Germany.

Science (New York, N.Y.)
|May 30, 2009
PubMed
概括

德洛索菲拉基因超性 (sxc) 编码了与O相关的N-乙糖胺 (O-GlcNAc) 转移酶 (Ogt). O-GlcNAc的修饰对于Polycomb组蛋白质在发育过程中保持转录抑制至关重要.

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