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通过调节脂肪酸代谢来增强CD8T细胞的记忆

Erika L Pearce1, Matthew C Walsh, Pedro J Cejas

  • 1Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

Nature
|June 5, 2009
PubMed
概括

瘤亡因子受体相关因子6 (TRAF6) 通过调节脂肪酸代谢,对于产生长寿命的CD8记忆T细胞至关重要. 抗糖尿病药物梅特福明恢复了记忆细胞的产生,并增强了抗癌疫苗的疗效.

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