记忆CD8T细胞的磨损
Raymond M Welsh1, Liisa K Selin
1Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA. raymond.welsh@umassmed.edu
Nature
|June 5, 2009
概括
重复免疫可以提高记忆CD8T细胞,而不会损害现有的记忆细胞. 然而,多次感染可能会减少记忆T细胞的总数,影响未来的疫苗接种策略.
科学领域:
- 免疫学 免疫学 免疫学
- 疫苗学 疫苗学 疫苗学
背景情况:
- 保持免疫记忆对于终身对病原体的保护至关重要.
- CD8 T 细胞在适应性免疫和免疫记忆中发挥着至关重要的作用.
- 现有研究对重复免疫接种对记忆T细胞群的影响提出了相互矛盾的发现.
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