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Updated: Jun 22, 2026

In Vitro Differentiation of Naive CD4+ T Cells into Pathogenic Th17 Cells in Mouse
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哈洛富基通过激活氨基酸饥饿反应来抑制TH17细胞分化

Mark S Sundrud1, Sergei B Koralov, Markus Feuerer

  • 1Department of Pathology, Harvard Medical School and Immune Disease Institute, Boston, MA 02115, USA.

Science (New York, N.Y.)
|June 6, 2009
PubMed
概括

哈洛基通过激活氨基酸饥饿反应 (AAR) 来选择性地抑制炎症性T辅助者17 (TH17) 细胞分化. 这种有针对性的方法可以在没有广泛的免疫抑制的情况下预防自身免疫病理,提供了一个有前途的治疗策略.

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