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相关概念视频

Urinary Bladder01:23

Urinary Bladder

The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
Nursing Assessment of the Genitourinary System II: Inspection and Palpation01:26

Nursing Assessment of the Genitourinary System II: Inspection and Palpation

The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...

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相关实验视频

Updated: Jun 22, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
07:48

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

Published on: December 1, 2013

膀癌是一种癌症.

Donald S Kaufman1, William U Shipley, Adam S Feldman

  • 1Department of Medicine, the Claire and John Bertucci Center for Genitourinary Cancers, Massachusetts General Hospital, Boston, MA 02114, USA. dskaufman@partners.org

Lancet (London, England)
|June 13, 2009
PubMed
概括
此摘要是机器生成的。

膀癌从不危及生命的表面瘤到致命的肌肉侵入性疾病各不相同. 治疗范围从静脉内疗法和手术到膀保护策略和化疗.

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An Orthotopic Model of Murine Bladder Cancer
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Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
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An Orthotopic Model of Murine Bladder Cancer
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科学领域:

  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科
  • 在瘤学瘤学.

背景情况:

  • 膀癌是一种异质性疾病,具有明显的临床行为.
  • 表面瘤复发但不那么危及生命,而肌肉侵入性疾病带来高死亡风险.
  • 无痛的血是主要症状,通过细胞学和通过尿道切除进行诊断.

研究的目的:

  • 审查目前对膀癌的理解和治疗.
  • 讨论膀癌不同阶段的诊断方法和治疗选择.
  • 探索新兴的治疗方法,包括膀保护,化疗,向疗法和分子进步.

主要方法:

  • 审查关于膀癌诊断和治疗的当前文献.
  • 对表面和肌肉侵入性膀癌的标准护理进行讨论.
  • 探索膀保护技术和全身疗法.

主要成果:

  • 静脉内治疗对 carcinoma in situ 和高度非肌肉侵入性瘤是有效的.
  • 带有尿路转移的激进细胞静态切除术是肌肉侵入性疾病的标准.
  • 膀保护和各种化疗剂显示出有前途.

结论:

  • 膀癌的管理需要根据疾病阶段进行量身定制的方法.
  • 化疗,向治疗和分子生物学方面的进步正在改善治疗选择.
  • 生活质量是尿路转移和治疗规划的关键考虑因素.