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Updated: Mar 30, 2026

Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System
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RIP1-RIP3复合体的酸化驱动组合调节了被编程的和病毒诱导的炎症

Young Sik Cho1, Sreerupa Challa, David Moquin

  • 1Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

Cell
|June 16, 2009
PubMed
概括

激酶RIP3对于编程性亡,细胞死亡途径至关重要. RIP3激活了RIP1酸化,启动了病毒感染期间炎症反应至关重要的级联反应.

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