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Updated: Jun 22, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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乙转移酶介导的聚基胺从真菌大合成酶释放出来

Xinkai Xie1, Michael J Meehan, Wei Xu

  • 1Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, California 90095, USA.

Journal of the American Chemical Society
|June 18, 2009
PubMed
概括

研究人员阐明了真菌酶LovF如何使用乙转移酶LovD释放产物. 这种由乙转移酶介导的释放机制提高了生产降胆固醇药物洛瓦斯塔丁的催化效率.

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