A McGarry Houghton1, William O Hartzell, Clinton S Robbins

  • 1Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA. houghtonm@dom.pitt.edu

Nature
|June 19, 2009
PubMed
概括

矩阵金属蛋白酶12 (MMP12) 通过破坏细胞膜直接杀死细菌. MMP12对于巨细胞的抗菌防御至关重要,其碳氧终端域调解了这种活动.

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