微生物对环境变化的自适应预测
Amir Mitchell1, Gal H Romano, Bella Groisman
1Department of Molecular Genetics, Weizmann Institute of Science Rehovot 76100, Israel.
Nature
|June 19, 2009
概括
诸如大肠杆菌和大肠杆菌 (Saccharomyces cerevisiae) 这样的微生物可以预测环境变化,这种特征可以改善它们的生存. 这种预期是通过刺激的时间顺序来学习的,建议它.
科学领域:
- 微生物学 微生物学
- 进化生物学 进化生物学
- 分子生物学分子生物学
背景情况:
- 微生物息地可以是不可预测的或可预测的,允许适应环境变化.
- 有机体可能会根据它们的时间顺序进化以预测环境刺激,类似于帕夫洛夫的条件.
研究的目的:
- 调查模拟微生物中的环境变化预测,大肠杆菌和麦芽菌.
- 确定预期是否是一种适应性特征,并了解其分子基础.
主要方法:
- 在受控的环境刺激下研究大肠杆菌和大肠杆菌.
- 利用实验室进化实验来观察条件反应的变化.
- 分析基因调节网络,以了解预测的分子机制.
主要成果:
- 已经证明,对早期环境刺激的预暴露会在遇到后续刺激时提高健康状况.
- 在仅暴露于初始刺激的大肠杆菌菌株中观察到条件反应的丧失.
- 揭示了调节网络嵌入刺激的时间顺序,早期的刺激预先诱导后来的基因.
结论:
- 环境预测是一种在微生物进化过程中选择的适应性特征.
- 环境刺激的时间顺序被整合到微生物调节网络中.
- 预测环境变化可能是一个无处不在的生物现象.
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