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Updated: Jun 22, 2026

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
10:10

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

Published on: March 31, 2019

多能因子Oct4与Ctcf相互作用,并控制X染色体对配和计数

Mary E Donohoe1, Susana S Silva, Stefan F Pinter

  • 1Howard Hughes Medical Institute, USA.

Nature
|June 19, 2009
PubMed
概括

一个关键的多能性因子Oct4通过调节同类染色体配对和计数来启动X染色体失活 (XCI). 这一发现揭示了Oct4

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