Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Pedigree Analysis01:35

Pedigree Analysis

78.8K
Overview
78.8K
Transduction01:16

Transduction

3.0K
Among the three main modes of HGT—transformation, conjugation, and transduction—transduction is unique in that it is mediated by bacteriophages, or bacterial viruses.Transduction occurs in two ways. Generalized transduction occurs during the lytic cycle of a bacteriophage infection. In this process, bacteriophages infect bacterial cells, replicate within them, and ultimately cause cell lysis, releasing newly assembled virions. Occasionally, random fragments of the bacterial genome...
3.0K
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

2.0K
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
2.0K
Evolutionary Processes in Microbes01:26

Evolutionary Processes in Microbes

202
Microbial evolution occurs rapidly due to short generation times and a variety of genetic processes, including horizontal gene transfer, mutation, recombination, and genetic drift. These mechanisms collectively enable microbes to adapt swiftly to changing environments.Horizontal gene transfer (HGT) allows genes to move between different species and occurs through three main mechanisms: conjugation, transformation, and transduction. Conjugation involves direct cell-to-cell contact for DNA...
202
Evolution of New Traits in Microbes01:24

Evolution of New Traits in Microbes

199
Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...
199
Evolution of Microbial Genome01:08

Evolution of Microbial Genome

110
Microbial genome evolution is a highly dynamic process shaped by continual gene gain and loss across species and strains. This genomic flexibility allows microorganisms to adapt rapidly to environmental pressures and interactions with other organisms. Central to understanding this diversity is the distinction between the core and pan genomes.The core genome comprises the genes shared by all sampled strains of a species, representing essential functions needed for fundamental cellular processes.
110

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Simultaneous measurements of translation rate and transcriptome uncovers linked regulation within an active bacterial cell population.

Science advances·2026
Same author

In vivo spatial coordination with synthetic paracrine signaling.

bioRxiv : the preprint server for biology·2026
Same author

Mapping and engineering the human cell-cell interactome.

Nature biotechnology·2026
Same author

Programmable pathway profiles reveal signaling principles of TGF-β superfamily receptors.

bioRxiv : the preprint server for biology·2026
Same author

Genome-wide chromatin recording resolves dynamic cell state changes.

bioRxiv : the preprint server for biology·2026
Same author

Initiation of swarming in <i>Bacillus subtilis</i> as a resolution for the sorites paradox in bacteria.

Proceedings of the National Academy of Sciences of the United States of America·2026

相关实验视频

Updated: May 5, 2026

Tractable Mammalian Cell Infections with Protozoan-primed Bacteria
13:54

Tractable Mammalian Cell Infections with Protozoan-primed Bacteria

Published on: April 2, 2013

10.1K

部分透性促进细菌的发育进化.

Avigdor Eldar1, Vasant K Chary, Panagiotis Xenopoulos

  • 1Howard Hughes Medical Institute and Division of Biology and Department of Applied Physics, California Institute of Technology, Pasadena, California 91125, USA.

Nature
|July 7, 2009
PubMed
概括

细菌细菌中的突变可以导致罕见的双胞胎子形成. 对这一过程的遗传控制,称为部分透,为发育进化和新特征的出现提供了洞察力.

科学领域:

  • 微生物学 微生物学
  • 发育生物学 发展生物学
  • 进化生物学 进化生物学

背景情况:

  • 发育过程通常在同源种群中产生统一的结果.
  • 部分透性,即突变对个体的影响不同,是已知的现象,但不太了解.
  • 控制替代细胞命运及其频率演变的机制仍然不清楚.

研究的目的:

  • 为了研究在 Bacillus subtilis 胞突变突变体中的随机细胞命运决定.
  • 了解遗传网络如何控制部分透和替代命运.
  • 探索发育途径的进化潜力.

主要方法:

  • 分析Bacillus subtilis变种突变体的变种突变体与改变的区间间信号传递.
  • 染色体复制和分离的遗传操纵.
  • 时间间隔显微镜观察B. subtilis和Clostridium oceanicum中的分泌动态.

主要成果:

  • 在B. subtilis突变体中确定了一种控制多个替代细胞命运的随机过程.
  • 证明了对这些突变命运的透的遗传控制,包括罕见的双胞胎子形成.
  • 表明,综合信号和复制扰动协同增加双胞胎子透率.

更多相关视频

Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains
06:45

Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains

Published on: January 18, 2014

8.0K
Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance
09:00

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Published on: May 2, 2018

11.1K

相关实验视频

Last Updated: May 5, 2026

Tractable Mammalian Cell Infections with Protozoan-primed Bacteria
13:54

Tractable Mammalian Cell Infections with Protozoan-primed Bacteria

Published on: April 2, 2013

10.1K
Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains
06:45

Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains

Published on: January 18, 2014

8.0K
Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance
09:00

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Published on: May 2, 2018

11.1K
  • 在野生类型的Clostridium oceanicum中观察到类似的双胞胎分泌,这表明保存机制.
  • 结论:

    • 细胞命运决定中的随机性可以促进发育进化.
    • 部分透性允许在低频率下初步表达新的特征.
    • 基因参数的调整可以稳定和增加新的发育结果的透率.
    • 这项研究为理解发育状态之间的进化过渡提供了一个模型.