在腹腔大动脉动脉瘤修复后改善了长期生存率
Kevin Mani1, Martin Björck, Jonas Lundkvist
1Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University Hospital, Uppsala, Sweden. kevin.mani@surgsci.uu.se
Circulation
|July 8, 2009
概括
在完整的腹腔大动脉瘤 (AAA) 修复后的长期存活率有所改善,即使患者人群年龄较大,并有更多的并发症. 破裂的AAA修复的生存率随着时间的推移而保持稳定.
科学领域:
- 血管外科 血管外科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在过去的二十年中,腹腔大动脉动脉瘤 (AAA) 的治疗方法有了显著的进化.
- 了解长期生存趋势对于评估治疗疗效至关重要.
研究的目的:
- 分析腹腔大动脉瘤 (AAA) 修复后的长期生存时间趋势.
- 为了比较不同患者人口统计和治疗期之间的生存结果.
主要方法:
- 从瑞典血管注册 (1987-2005) 中回顾分析了8663个完整的和4171个破裂的AAA修复.
- 从国家人口登记处获得的死亡率数据.
- 计算了原始和相对生存率 (根据年龄,性别,日历年份进行调整),不包括90天死亡率用于相对生存率分析.
主要成果:
- 对于完整的AAA修复,从1987-1999年到2000-2005年 (增加4.7%) 的5年相对存活率有所改善.
- 在男性与女性,八十岁与年轻患者的生存率有所改善.
- 在开放式和内血管修复方法之间没有观察到相对5年生存时间的显著差异.
- 对于破裂的AAA修复,相对5年生存率在时间段,性别和年龄组中保持稳定.
结论:
- 完整的AAA修复后的长期存活率有所改善,尽管伴随疾病的老年患者比例越来越高.
- 在研究期间,破裂的AAA修复的生存结果一直保持一致.
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