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Updated: Jun 21, 2026

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
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化学选择性结合在基于多糖的颗粒的功能化中

Tristan T Beaudette1, Joel A Cohen, Eric M Bachelder

  • 1Department of Chemistry, University of California, Berkeley, California 94720-1460, USA.

Journal of the American Chemical Society
|July 14, 2009
PubMed
概括

研究人员开发了一种新方法,可以轻松修改德克斯微粒表面. 这一策略可以实现向药物递送,显著增加非细胞细胞中使用功能化颗粒的基因表达.

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Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...