通过信号依赖的转录延长来控制可诱导的基因表达

Diana C Hargreaves1, Tiffany Horng, Ruslan Medzhitov

  • 1Howard Hughes Medical Institute and Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.

Cell
|July 15, 2009
PubMed
概括

主要响应基因 (PRG) 具有预组装的转录机制,用于快速基因表达. 它们的诱导依赖于信号依赖的延长和mRNA处理,由Brd4-介导的P-TEFb招募促进.

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