相关实验视频

Updated: Jun 20, 2026

Development of a Human Preclinical Model of Osteoclastogenesis from Peripheral Blood Monocytes Co-cultured with Breast Cancer Cell Lines
06:00

Development of a Human Preclinical Model of Osteoclastogenesis from Peripheral Blood Monocytes Co-cultured with Breast Cancer Cell Lines

Published on: September 13, 2017

突变的C-CBL瘤抑制剂在髓状瘤中获得功能

Masashi Sanada1, Takahiro Suzuki, Lee-Yung Shih

  • 1Cancer Genomics Project, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

Nature
|July 22, 2009
PubMed
概括

在骨髓瘤瘤中,获得的单亲异构 (aUPD) 与C-CBL瘤抑制剂中的新型功能获取突变有关. 这些突变增强了造血干细胞中的细胞因子敏感性,推动了癌症的发展.

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