相关实验视频
可修改的生活方式因素与终身心力衰竭风险之间的关系
Luc Djoussé1, Jane A Driver, J Michael Gaziano
1Division of Aging, Brigham and Women's Hospital and Harvard Medical School, 1620 Tremont St, Third Floor, Boston, MA 02120, USA. ldjousse@rics.bwh.harvard.edu
JAMA
|July 23, 2009
概括
采用健康的生活习惯,如保持正常体重,不吸烟和运动,可以显著降低男性一生心力衰竭的风险. 坚持多个因素提供了最大的保护.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 公共卫生 公共卫生
背景情况:
- 心力衰竭是一个重要的终身风险,在40岁时影响大约五分之一的人.
- 对于可修改的生活方式因素对心力衰竭的长期风险的影响的理解有限.
研究的目的:
- 调查可修改的生活方式因素与患心力衰竭的终身风险之间的关联.
- 这项研究集中在一大群看似健康的男性身上.
主要方法:
- 使用来自医生健康研究I (1982-2008) 的数据进行了前性队列研究.
- 这项研究包括20900名男性,评估了六个可修改的生活方式因素:体重,吸烟状态,运动习惯,酒精消耗以及早餐谷物,水果和蔬菜的摄入量.
- 主要结局指标是心力衰竭的终身风险.
主要成果:
- 在平均22年4年的随访期间,1200名男性患上心力衰竭.
- 40岁时心力衰竭的整体终身风险为13.8%,在没有心力衰竭的人群中,到80岁时降至10.6%.
- 坚持健康的生活方式因素,无论是个人还是集体,都与心力衰竭的终身风险降低有关. 坚持四个或更多健康因素的男性风险最低 (10.1%).
结论:
- 在这组健康男性中,采用健康的生活方式与终身心力衰竭风险降低有关.
- 促进健康习惯可能是预防终身心力衰竭的关键策略.
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