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Updated: Jun 21, 2026

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
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RNA聚合酶III检测细胞质DNA并通过RIG-I通路诱导I型干扰子

Yu-Hsin Chiu1, John B Macmillan, Zhijian J Chen

  • 1Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.

Cell
|July 28, 2009
PubMed
概括

细胞质DNA通过RNA聚合酶III (Pol-III) 转化为5'-三酸RNA (5'-pppRNA),从而触发干扰素反应. 然后,这种RNA激活RIG-I通路,突出显示Pol-III.

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