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Updated: May 7, 2026

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
11:25

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice

Published on: April 1, 2015

MafB限制了血造干细胞的M-CSF-依赖的髓状干细胞承诺划分

Sandrine Sarrazin1, Noushine Mossadegh-Keller, Taro Fukao

  • 1Centre d'Immunologie de Marseille-Luminy, Université Aix-Marseille, Campus de Luminy, Case 906, 13288 Marseille Cedex 09, France.

Cell
|July 28, 2009
PubMed
概括

转录因子MafB控制了造血干细胞 (HSC) 的分裂,特别限制了髓状血统的承诺. 由于MafB缺乏,因此提高了HSC对M-CSF的敏感性,从而促进了骨髓单细胞的重新填充.

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