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普列尼林对于调节神经递质释放至关重要

Chen Zhang1, Bei Wu, Vassilios Beglopoulos

  • 1Center for Neurologic Diseases, Brigham & Women's Hospital, Program in Neuroscience, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|July 31, 2009
PubMed
概括

前列尼林基因突变导致家族性阿尔茨海默病. 这项研究表明,前素对前神经突触功能至关重要,影响神经递质释放和突触可塑性,这表明阿尔茨海默病的发病过程中早期的前神经突触功能障碍.

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