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Updated: May 11, 2026

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
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Published on: June 15, 2017

IRE1α激酶激活模式控制替代性内核酶输出,以确定分离的细胞命运

Dan Han1, Alana G Lerner, Lieselotte Vande Walle

  • 1Department of Medicine, University of California, San Francisco, San Francisco, CA 94143-2520, USA.

Cell
|August 12, 2009
PubMed
概括

展开的蛋白质响应 (UPR) 可以触发细胞死亡在细胞内网膜 (ER) 压力. 激酶抑制剂可以通过改变IRE1alpha RNase活性来阻止这种亡,从而促进细胞存活.

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