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Updated: Jun 21, 2026

Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry
05:45

Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry

Published on: June 8, 2021

用上下电子捕获解离的/交换质谱法,用于表征17kDa蛋白质的结构转变

Jingxi Pan1, Jun Han, Christoph H Borchers

  • 1Department of Chemistry, The University of Western Ontario, London, ON, N6A 5B7, Canada.

Journal of the American Chemical Society
|August 13, 2009
PubMed
概括

本研究介绍了用于蛋白质结构分析的上下电子捕获解离 (ECD) 质谱法 (MS). 与传统技术相比,这种先进的方法为胺H/D交换 (HDX) 研究提供了更高的分辨率.

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