缺血性左心综合征是什么意思
David J Barron1, Mark D Kilby, Ben Davies
1Department of Cardiac Surgery, Birmingham Children's Hospital, Birmingham, UK. david.barron@bch.nhs.uk
Lancet (London, England)
|August 18, 2009
概括
缺血性左心综合征 (HLHS) 管理已经从致命发展到通过手术干预可以治疗. 目前的策略包括分阶段的手术,新生儿移植和混合技术,为受影响的儿童提供更好的结果.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 遗传性心脏缺陷 遗传性心脏缺陷
- 新生儿心脏手术 新生儿心脏手术
背景情况:
- 低发性左心综合征 (HLHS) 是一种严重的先天性心脏缺陷,其特点是左心部发育不良.
- 从历史上看,HLHS的预后几乎是致命的,需要医疗和外科护理的进步.
- 由于HLHS的复杂性,需要从出生到成年期进行专业的多学科管理.
研究的目的:
- 审查目前对低可塑性左心综合征的外科治疗策略.
- 讨论不断发展的治疗选择,包括分阶段缓解,移植和混合方法.
- 突出管理HLHS患者进入青春期和成年期的持续挑战.
主要方法:
- 对HLHS的手术技术的审查,重点是使用右心室进行分阶段的息.
- 讨论替代治疗方案,如新生儿心脏移植.
- 探索结合手术和干预方法的创新混合程序.
主要成果:
- 手术干预显著提高了HLHS的生存率,改变了其以前致命的前景.
- 阶段性程序,右心室支持两个循环,是当前管理的基石.
- 新生儿移植和混合技术提供了替代或辅助的治疗途径.
结论:
- 在HLHS的手术和重症监护管理方面取得了重大进展,改善了患者的预后.
- 尽管取得了进展,但在HLHS幸存者的长期护理中,当他们过渡到成年时,他们面临着持续的挑战.
- 持续创新手术技术和综合护理对于优化HLHS患者的治疗结果至关重要.
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