息护理干预对晚期癌症患者临床结果的影响:项目 ENABLE II随机对照试验
Marie Bakitas1, Kathleen Doyle Lyons, Mark T Hegel
1Department of Anesthesiology, Section of Palliative Medicine, Dartmouth Medical School, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA. marie.bakitas@dartmouth.edu
JAMA
|August 20, 2009
概括
护理主导的息护理干预改善了晚期癌症患者的生活质量和情绪. 然而,它并没有显著降低症状强度或医疗资源利用率.
科学领域:
- 在瘤学瘤学.
- 抚慰性护理是一种缓解性护理.
- 护理研究 护理研究
背景情况:
- 有限的随机对照试验存在于晚期癌症患者的息护理干预措施.
- 先进的癌症护理需要干预措施来改善患者的治疗结果和生活质量.
研究的目的:
- 评估护理主导干预对晚期癌症患者的生活质量,症状强度,情绪和资源使用的影响.
- 为了评估多组件心理教育干预 (Project ENABLE) 与常规护理相比的有效性.
主要方法:
- 一项随机对照试验,涉及322名癌症晚期患者.
- 干预组接受了一项由护士领导的精神教育计划 (Project ENABLE),而对照组接受了通常的护理.
- 测量结果包括生活质量,症状强度,情绪和医疗资源利用率 (医院日,ICU日,急救诊所).
主要成果:
- 与通常护理相比,干预组的生活质量 (P=.02) 和情绪 (P=.02) 显著改善.
- 症状强度呈现改善趋势 (P=.06),但没有达到统计学意义.
- 干预和通常护理组之间在医疗保健资源利用方面没有显著差异.
结论:
- 护士主导的息护理干预可以提高晚期癌症患者的生活质量和情绪.
- 这项干预措施在减少症状强度或医疗资源使用方面没有显著的好处.
- 与瘤护理相结合的并发息护理需要进一步研究,以优化患者的福祉.
相关概念视频
Treatment Resistant Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Cancer Survival Analysis
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
